If you cannot make calls via a SIP route, it will be necessary to verify if that route's IP address is allowed at the firewall.
If it is not allowed, you will have to insert a new firewall rule allowing access to the UDP port 5090.
When the SIP route is set with a hostname, it will be necessary to identify which IP address are assigned to it. These IP addresses have to have firewall rules allowing access to UDP port 5090.
Every time you add a new SIP route make sure to allow access by adding a firewall rule.